Joint & Bone Initiative

Dr. Cheryle Seguin

Research Areas

Human Ebryonic Stem Cell Research, Cell Lineage Specification

Dr. Séguin obtained her BSc (1999) and MSc (2001) from The University of Western Ontario and her PhD in the area of cell biology and tissue engineering from the University of Toronto (2005).

Following this, Dr. Séguin became a postdoctoral fellow under the supervision of Dr. Janet Rossant at the SickKids Hospital, working in the field of early mammalian development and stem cell biology. While at SickKids Hospital, Dr. Séguin assumed the role of Interim Manager and helped establish the Ontario Human Induced Pluripotent Stem Cell (iPSC) Facility, an endeavour funded by the Ontario Ministry of Innovation and spearheaded by Dr. James Ellis and Dr. Bill Stanford. In 2009, Dr. Séguin was recruited to the Department of Physiology and Pharmacology at The University of Western Ontario.  She is Co-Director of the Joint Motion Program at Western and Course Director for MSK 9000.

Dr. Séguin's lab studies are focused on using human embryonic stem cells to understand the mechanisms regulating early development and cell lineage specification.  Using genetic tools to induce the expression of developmentally relevant transcription factors, studies are aimed towards the guided differentiation of human embryonic stem cells (HESC) towards lineage committed, tissue-specific progenitor cells.


Recent Publications