BJI members are focused on understanding the initiation and progression of joint degeneration, bone loss, the role of abnormal biomechanics, and learning more about how cells respond to their local mechanical environment disciplines
For example, the coordinated activity of cell and molecular biologists, engineers, and clinical investigators brings together studies in cell cultures, animal models, and clinical populations.
Striving to develop sophisticated magnetic-resonance imaging techniques, micro-computed tomography, and radiographic analysis systems, as well as new strategies to prevent the onset and progression of various MSK conditions, BJI investigators integrate their expertise and state-of the-art facilities
This critical mass of research expertise presents a unique opportunity to combine:
advanced imaging technologies
new contrast agents
biochemical/genetic markers
patient-reported and performance-based measures of pain and function
forensic methodologies and anthropological investigations
New biologics and pharmaceuticals, novel scaffolds for tissue regeneration, innovative joint replacement components, and next-generation rehabilitative and assistive devices are envisioned to:
enhance bone growth
encourage implant integration
improve recovery from trauma and surgery
effectively evaluate outcomes
Crucial to meeting this objective is the integration of BJI experts in:
injury prevention
lifestyle changes
work modifications
diet and exercise
basic sciences (chemistry, materials, cell and molecular biology)