Animal Models, Clinical Outcomes, Drug Delivery, Molecular & Cell Biology, Muscle Disorders, Musculoskeletal Imaging, Personalized Medicine, Regenerative Medicine
Dr. Hoffman obtained her Ph.D. from the University of Saskatchewan in 2000. She went on to complete several postdoctoral positions that culminated in a unique skill set in stem cell biology, classic cell/molecular biology, and non-invasive multi-modality imaging. Imaging modalities include positron emission tomography [PET], dynamic contrast-enhanced computed tomography [DCE-CT], high frequency 3D ultrasound [HFU]/echocardiography, and optical/bioluminescense imaging . She is currently one of few Canadian researchers poised to take advantage of the recent opening of the PETtracer Cyclotron and PET-radiochemistry facility in London. Dr. Hoffman was appointed as a Lawson Imaging Scientist in the Fall of 2009, and as Asistant Professor in the Departments of Medical Biophysics , Western University (Fall 2009) and Anatomy & Cell Biology, Western University (Spring 2010). Capitalizing on the breadth of her multidisciplinary experience, Dr. Hoffman's current research interests lie in Molecular Imaging and Cell Therapeutics for the treatment of both the skeletal and cardiac manifestations of Duchenne muscular dystrophy (DMD). Specifically, her group aims to develop objective and quantitative non-invasive imaging technologies to track stem/progenitor cell fate following transplantation into mouse models of DMD.
Her growing expertise in this area of research has been recognized by her being awarded a Stem Cell Network (SCN) Transitional Research Grant in 2008. She has additionally held internal operating funds (IRF) with Lawson (2009-2010), and a CIHR Priority Announcement from the Institute of Musculoskeletal Health and Arthritis in 2010. She currently holds another Lawson IRF (2011-2012), a NSERC Discovery Grant (2011-2016), and a HSFO Grant-In-Aid (2012-2014).